NAD+ MULTI-PATHWAYS SYNTHESIS

Having optimum NAD+ levels is vital for healthy energy, fat and glucose metabolism, insulin regulation, DNA repair, inflammation response, and a host of other health effects. NAD+ levels and activity are elevated by four main pathways, and two additional secondary pathways from the botanicals in the Kimia NAD+ Booster. The following is a description of each NAD+ boosting pathway and which of the following herbs in the formula are activated by that pathway.

HOW IT WORKS

NAMPT the enzyme that controls how much NAD+ is synthesized. Increasing the levels by using bioactives increases NAD+ levels. This can even occur without the use of NAD+ precursors and may be even better since it can enhance the recycling of NAD+ from niacinamide in the Salvage pathway. 

NAD+ is mainly synthesized by the Salvage Pathway in the human body which goes through two vital enzyme steps NAMPT and NMNT for its formation. NAMPT is the most important as the rate limiting enzyme. NAMPT decreases with age, however aerobic exercise has been shown to increase or restore NAMPT levels (de Guia, 2019). Observed evidence: Muscle-specific NAMPT knockout mice show an 85% decrease in muscle NAD+ levels, which causes muscle degeneration and progressive loss of muscle, strength and endurance capacity (Almeida, 2023). One of the most important enzymes that increases NAD+ levels

  NAD+ BOOST PATHWAY DEFINITION

One of the most important enzymes that increases NAD+ levels.