NAD + Booster
Powerful benefits
NAD+Anti-Aging Booster
Anti-aging Elixir
NAD+ is an essential compound for supporting our metabolism for a wide range of functions that help keep our bodies healthy and vibrant. As we age, we begin to produce less and less NAD+. Kimia NAD+ Boost is here to help maintain normal NAD+ levels.
NAD+ Benefits
NAD+ is essential for the production of Sirtuins that are the key to maintaining good health, especially in our later years. NAD+ also helps maintain healthy mitochondria function in the cell, reduces aging of stem cells that can differentiate into new tissue, and helps maintain a healthy heart and blood vessels.
Energy Metabolism
Energy metabolism is vital for powering all of our fundamental physiological functions, including muscle contraction, fat metabolism, thinking processes, cellular defenses, cell division, and reproduction. NAD+ helps maintain healthy mitochondria, which are the energy producers of the cell.
Support CD38 Inhibition
CD38 is an enzyme protein made in your body that is found on the surface of immune cells. It is known to lower NAD+ levels, so inhibition of CD38 can effectively boost NAD+ levels. There are many natural CD38 inhibitors in plant-based foods such as the flavonoids apigenin, luteolin, and quercetin found in parsley, apples, and artichoke.
Cognitive Support
Adequate levels of NAD+ are important as we age for maintaining the health of mitochondria, the energy producers of the cell. NAD+ is a key enzyme in the production of energy molecule ATP, which has been shown to be a vital part of our normal brain cellular function.
Immune Support
NAD+ is a natural component of a healthy immune response in the body. It is a critical agent in the metabolism and function of T cells, natural killer cells and macrophages, which are an important part of our natural defenses.
What does "Pathways activated" mean?
A single herb can contain over 500 active compounds, each capable of activating various biological pathways—specific sequences of actions within cells that address imbalances in the body. At Kimia, advanced formulation techniques assign roles to each herb, creating a synergistic blend that achieves multi-pathway activation more effectively than many other herbal products.
Pathways activated
NAMPT
NAD+ is mainly synthesized by the Salvage Pathway in the human body which goes through two vital enzyme steps NAMPT and NMNT for its formation. NAMPT is the most important as the rate limiting enzyme....
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AMPK
Activation of AMPK increases the NAD+/NADH ratio. An increase in NAD+ after exercise supports the idea that changes in NAD+ levels are based on AMPK increasing SIRT1 activity. AMPK enhances SIRT1 activity through increasing cellular...
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CD-38 Inhibition (NAD+)
A compound produced in the body called CD38 provides a counteracting balance to NAD+ and Sirtuins, and can be produced to problematic excess as a result of aging, viral infection, or chronic inflammation. Inhibiting CD38...
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Sirtuin-1 (NAD+)
SIRT1 boosts NAD+ by acting on NAMPT found inside the cells (iNAMPT) facilitating it’s secretion from fat cells (adipocytes) into the extra-cellular space outside of cells where it becomes known as eNAMPT. SIRT1 enhances eNAMPT...
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DNA damage blockage
Oxidative stress is a cause of NAD+ depletion, and aging increases both oxidative stress and NAD+ depletion as well as the loss of SIRT1 activity. Strong positive correlations were also observed between lipid peroxidation and...
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Lower inflammatory response support
Since chronic and excessive inflammation depletes NAD+ through increased CD38 levels, another way of boosting NAD+ is to support a lower inflammation response to reduce CD38+ levels by using inflammation-support botanicals. (Poljšak, 2023).
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NAD de novo Synthesis
Besides the two main NAD+ synthesis pathways the body uses to form NAD+ from its precursors (Salvage pathway from niacinamide vit. B3) and the Preiss-Handler pathway (from dietary niacin), the third pathway, known as the...
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PARP Inhibition
NAD+ is depleted when extensive DNA damage causes activation of a DNA repair enzyme known as PARP (poly-ADP-ribosyl Polymerase) found in the cell nucleus. Increased PARP activity and DNA damage are elevated with aging. PARP...
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